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2024 | OriginalPaper | Buchkapitel

Sicherer Umgang mit gefährlichen Chemikalien im Durchfluss

verfasst von : Md Taifur Rahman, Thomas Wirth

Erschienen in: Flow-Chemie für die Synthese von Heterocyclen

Verlag: Springer International Publishing

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Zusammenfassung

Die Durchflusschemie hat sich im Laufe des letzten Jahrzehnts zu einem hervorragenden Werkzeugkasten für anspruchsvolle chemische Umwandlungen entwickelt. Hochexotherme und kinetisch schnelle Reaktionen sind selbst im kleinen Maßstab schwierig zu handhaben, während jede Hochskalierung erhebliche Risiken birgt, wenn herkömmliche Reaktoren in Betracht gezogen werden. Die Durchflusschemie ermöglicht eine exquisite Kontrolle über Mischsequenzen, Reaktionszeit und Abschreckung, die letztendlich den Weg für die Feinabstimmung der chemischen Reaktivität in ,Raum und Zeit‘ ebnet. Dieses Kapitel beschreibt die jüngsten Fortschritte der Durchflusschemie bei der Kontrolle und sogar Entdeckung neuer Reaktivitäten von hochgefährlichen chemischen Arten und instabilen Zwischenprodukten. Dieses Kapitel fasst faszinierende aktuelle Beispiele zusammen, die die Kraft der Durchflusschemie demonstrieren, um allgemein bekannte kryogene Reaktionen bei oder nahe Raumtemperatur, sicheres Handling und In-situ-Produktion von gefährlichen oder giftigen Reagenzien für chemische Umwandlungen durchzuführen, die in herkömmlichen Reaktoren allgemein als unsicher gelten.

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Vorheriges Kapitel Durchflusschemie als Werkzeug zur Arzneimittelforschung: eine medizinchemische Perspektive

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Titel: Sicherer Umgang mit gefährlichen Chemikalien im Durchfluss
verfasst von: Md Taifur Rahman
Thomas Wirth
Verlag: Springer International Publishing
Buch: Flow-Chemie für die Synthese von Heterocyclen
Print ISBN: 978-3-031-51911-6

Electronic ISBN: 978-3-031-51912-3

Copyright-Jahr: 2024
DOI: https://doi.org/10.1007/978-3-031-51912-3_8